The PXN Antibody (Y118) from MyBioSource.com is a Rabbit Polyclonal antibody to Paxillin, and Pxn. This antibody recognizes Human antigen. The PXN Antibody (Y118) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
PXN is a cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. PXN contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk)